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Aminoglycoside toxicity may be enhanced in patients taking lysine supplementation. Sufferers with liver and kidney impairment should avoid supplementation with lysine. Use of calcium supplements with lysine may be related to increased absorption and diminished elimination of calcium. Lysine may be dosed from 1 to 3 g daily to prevent or deal with herpes simplex infections, reserving the higher dosages for breakouts.
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Tie F, Banerjee R, Stratton CA, Prasad-Sinha J, Stepanik V, Zlobin A, Diaz MO, Scacheri PC, Harte PJ: CBP-mediated acetylation of histone H3 lysine 27 antagonizes drosophila polycomb silencing. Hornbeck PV, Kornhauser JM, Tkachev S, Zhang B, Skrzypek E, Murray B, Latham V, Sullivan M: PhosphoSitePlus: a comprehensive useful resource for investigating the structure and function of experimentally determined publish-translational modifications in man and mouse.
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